Detailing of Tablet Coating
Tablet Coating
Tablet coating is a cycle where a thin layer of polymer is applied over a centre tablet, and the weight gain of the film might fluctuate from 1-5 % for film coating to 10-12% for enteric coating. Sugarcoating is likewise a kind of coating, yet in sugar coating, rather than a polymer layer, we utilise a sucrose solution for structuring a layer of sugar over the centre tablets.
We are all very well acquainted with the fundamental kinds of tablet coating, which are as follows,
- Sugarcoating
- Film coating
- Enteric coating
Sugarcoating is a kind of tablet coating in which a layer of sucrose or sugar is applied over the centre tablet. It is a multistage process, and tablet weight might be expanded up to 50-80% in the wake of coating.
Film coating is a quick delivery coating. It is a single-stage coating process. It is also a kind of tablet coating in which a polymer is utilised to form a layer over the tablet. In film coating, the concentration of polymer and other strong items utilised is 1-5%, so the heaviness of the tablet isn’t increased as much as in the case of sugar coating. Film coating is finished to safeguard the item from temperature, stickiness, and so on, and to veil the taste.
Enteric Coating is a kind of covering that is utilised to safeguard medications that are destroyed by the stomach’s corrosive environment. In this kind of coating, a layer of polymer is applied over the core tablet; however, the dissolvability of this polymer is pH-dependent, so we use polymers that don’t break down in an acidic environment, yet do in the small intestine.
Coating Suspension. To store the layer of polymer over the tablet core, we set up a suspension or dispersion of polymers and other excipients.
The following are the various parts of tablet coating:
- Polymer/Film former
- Solvent
- Plasticiser
- Colourants
- Opaquants
- Miscellaneous